Talking Telomeres

Telomeres are an essential part of human cells that affect how our cells age. The telomeres are the caps at the end of each strand of DNA that protect our chromosomes, just like the plastic tips at the end of shoelaces. Like the rest of a chromosome, including its genes, telomeres are sequences of DNA […]

hTERT Promoter

Telomerase reverse transcriptase (hTERT in humans) is a catalytic subunit of the enzyme telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex. Mutations occur at four specific sites in the hTERT promoter in 75% of glioblastomas and melanomas, but the mechanism by which the mutations affect […]