Mitochondria are found in every cell in our body. They are the part of the cell where cellular respiration and energy production occurs. They convert the carbohydrates and fats we eat into energy that our cells can use. This resulting fuel (energy) is called ATP (adenosine triphosphate) and every cell in our body uses it. Improved energy is a 4-step process and without healthy mitochondria, none of it would be possible.
PQQ (Pyrroloquinoline quinone) seems to modify oxidation in a cell after binding to some proteins, and this modulatory role it plays can alter the signaling processes that go on in a cell. Due to PQQ being a REDOX agent (capable of both reducing and oxidizing) it is not a pure antioxidant, but it is involved in a cyclical antioxidative cycle with an antioxidant enzyme known as glutathione.
If any part of the energy creation process is prevented or blocked by a deficiency in the mitochondria, it can’t produce the needed energy. As this continues to happen the body isn’t able to function properly, which only exacerbates the situation. Eventually, this can lead to fatigue and toxin buildup that can lead to disease.
The health and degeneration of our mitochondria can be affected by genetic mutations and oxidative stress caused by free radicals and aging. The resulting loss of mitochondrial function, from any of these cases, can lead to neurodegenerative disorders like Parkinson’s, Dementia, and Alzheimer’s.
While mitochondria degeneration affects various parts of the body in different ways, the brain is the most susceptible to it. Your brain requires a lot of energy to function. It’s also exposed to more oxygen, which makes it more likely to be affected by oxidative stress. With all of its energy requirements, the brain is less tolerant of any mitochondrial mutations or loss of function. This loss effects themselves in different ways but it’s usually in the form of cognitive decline and memory loss.
The goal is to calm down our immune system, avoid allergens, take away the source of oxidants and add in antioxidant nutrients. In addition to vitamins A, C, E, selenium, and zinc, magnesium and quercetin are also important. These are particularly helpful in asthma. Although the essential fats, particularly fish oils and evening primrose oil, have proven most helpful in inflammatory conditions. If a person has an unfavorable balance of oxidants to antioxidants even these can be oxidized and even make inflammation worse. Under these conditions it is best to remove allergens, add in antioxidant nutrients and restore the balance before adding in anti-inflammatory fish oils (omega 3 & 6 fats.
A generation of new neurons in the brain, and thereby new mitochondria, is not a process that our body easily undertakes. It must be stimulated. Science has begun to explore the ability of our body to generate new mitochondria and while vigorous exercise seems to hold some promise, it’s still not a guarantee. Research points to an antioxidant, PQQ (Pyrroloquinoline quinone) is a small molecule once thought to be a vitamin, although its actions in the human body are not related to this hypothesized vitamin-like mechanism. Via its actions as a REDOX agent in cells, it can modify signaling and is thought to support mitochondrial function.
Heal your Mitochondria
Phospholipid therapy, Digestive supplementation is recommended to increase the absorption of the phospholipids.