There are over 24,000 over the counter and prescription medications which are created with the assumption the entire population is a normal metabolizer; when the fact is nearly 70% of the population has an aberration within the first five major metabolic pathways most drugs use. Our testing covers about 80% of those medications.
The use of genotyping provides you with “invisible” genetic information on a patient’s propensity for a drug reaction which allows you to further objectify each individual’s treatment, prevent toxicity and minimize the risk of harm due to Adverse Drug Reactions (ADR). Our results can be interpreted generally within 60 seconds.
Awareness of the influence of gene variations on patient response to certain drugs can help physicians identify cases in which a patient isn’t responding as anticipated to a drug therapy.
For example, some pain relief medications such as codeine require a protein (an enzyme) produced in the liver called CYP2D6 for the drug to be used by the body, break it down and remove it. Variations in the information contained in the CYP2D6 gene determine how much of this enzyme is produced in the liver.
Everyone has small variations in their genes that do not cause any problem with the way that the gene works. Since these differences may influence drug metabolism or how the condition develops, the variations would need to be identified. This process is very difficult and time-consuming.
Atlanta, Georgia USA